Magnesium Threonate
Mentioned 6 times across 4 shows · first heard Oct 2025 on Huberman Lab.
The general take
Andrew Huberman recommends magnesium threonate as one of the top three sleep supplements, suggesting 145 milligrams can significantly help many people fall and stay asleep. Rhonda Patrick supports it as a form that crosses the blood-brain barrier, though she notes the evidence is limited and largely comes from animal studies. Both speak positively about it for sleep support.
About
Quick thinking: Want to stay sharp? Try magnesium L-threonate: this form of magnesium helped maintain executive function and “quick thinking” in clinical studies. · Short-term memory: magnesium L-threonate helps support your working or “short term” memory health, so you don’t forget where you put your car keys, etc. · Cognitive health: magnesium plays an important role in your brain, supporting cognitive function. Magnesium L-Threonate is a special form of magnesium well-studied for cognitive health. · Ingredients matter – We use the finest raw ingredients chosen for quality and purity. The majority of our products are non-GMO, gluten-free and manufactured in the USA with globally sourced ingredients, and a Certificate of Analysis is available for each.
Who said what
Andrew Huberman👍 Recommends
…sleep supplement supporting improved sleep quality and consistency
“There are supplements that for most people will greatly improve their ability to fall and stay asleep. And the three main supplements in that category or that kit of sleep supplements are magnesium threonate, so T-H-R-E-O-N-A-T-E. For many people, taking 145 milligrams of magnesium threonate can be very beneficial.”
Huberman Lab — Essentials: Sleep Toolkit for Optimizing Sleep & Sleep-Wake Timingat 28:23
Rhonda Patrick👍 Recommends
…rhonda patrick comparing different forms of magnesium for cognitive and sleep benefits
“If we're comparing magnesium bisglycinate or magnesium glycinate, depending on how many molecules of glycine are attached to the magnesium, compared to magnesium L3 and 8, the main difference here, and this is based on very limited amount of data, a lot of it animal data with respect to the magnesium 3 and 8, is that that form of magnesium is supposed to get into and cross the blood-brain barrier more readily and get into the brain better.”
Huberman Lab — The Best Vitality & Health Protocols | Dr. Rhonda Patrickat 38:36- DJ
Dr. Josh Axe👍 Recommends
…recommending magnesium threonate for sleep support
“My favorite, magnesium glycinate. Okay, magnesium threonate is also beneficial and so is a multi-cheleted form of magnesium that's more food-based.”
The Dr. Josh Axe Show — 4 Tips to Massively Improve Your SLEEP Qualityat 46:15 - SW
Shawn Wells👍 Recommends
…discussing optimal forms and dosing of magnesium supplementation
“Magnesium, you're probably not getting enough of in a multi. It just needs to be bigger doses. I'm a big fan of magnesium bisglycinate, magnesium glycinate or magnesium threonate. Those are really the two best forms are both amino acid chelates, meaning the amino acid helps the bioavailability glycine or threonate.”
The Dylan Gemelli Podcast — Episode #103 Featuring Shawn Wells! The MOST TRUSTED Name in Supplements! ASTONISHING INSIGHT from the wide world of supplements! Also discussions on Peptides, SARMS, Scams and MORE!at 44:08 - RL
Robert Love👍 Recommends
…exploring magnesium supplements that support cognitive function
“Magnesium threonate is really good. It's a smaller form of magnesium that can cross the blood-brain barrier. It's a little bit more expensive, but that's shown to be really helpful for the brain. Maybe I'll switch to that one. You could do both.”
Digital Social Hour — 10,000 Steps a Day Could Cut Alzheimer’s Risk in Half | Robert Love | DSH #1853at 08:05 - KS
Konstantina Stankovic👍 Recommends
…magnesium supplement formulation for hearing and brain protection
“What we now think is that magnesium threonate is most efficient in crossing the blood-brain barrier. So we think it's probably the best for hearing protection, but that study is yet to be conducted. I've been taking magnesium threonate for, gosh, well over a decade because I learned that it was the form that most readily crosses the blood-brain barrier.”
Huberman Lab — Protect & Improve Your Hearing & Brain Health | Dr. Konstantina Stankovicat 37:52
Listener reviews
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