Alpha-GPC
Mentioned once across 1 show · first heard Jul 2025 on Huberman Lab.
studentscognitive enhancementfocus
The general take
Andrew Huberman discusses alpha-GPC as something he personally takes, framing it as potentially helpful for managing excess mental capacity in intellectually engaged and physically active people—suggesting it might help redirect what could otherwise feel like anxiety or ADHD symptoms. However, the quote cuts off before he fully explains his reasoning or results.
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Who said what
Andrew Huberman👍 Recommends
…discussing acetylcholine-enhancing compound for cognitive focus and learning
“One such compound is so-called alpha GPC, which is a form of choline and increases acetylcholine transmission. Dosages as high as 1200 milligrams per day have been shown to offset some of the effects of age-related cognitive decline, improve cognitive functioning. People that don't have age-related cognitive decline, typically when people are using alpha GPC to study or to enhance learning of any kind, they will take somewhere between 300 and 600 milligrams.”
Huberman Lab — Essentials: ADHD & How Anyone Can Improve Their Focusat 38:35
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