Black Pepper Extract
Mentioned once across 1 show · first heard Dec 2025 on Huberman Lab.
The general take
Kyle Gillett views black pepper extract as a potent bioavailability enhancer for turmeric/curcumin, to the point where he recommends people with low DHT or androgen receptor insensitivity avoid it. It's positioned more as a tool with specific contraindications rather than a general supplement recommendation.
About
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Who said what
Kyle Gillett💬 Mentioned
…discussing how black pepper extract may inhibit DHT conversion in men
“Yeah, turmeric, black pepper extract. Do you recommend that people avoid curcumin and turmeric for that reason? If someone's DHT is already low or if they have somewhat insensitive androgen receptor via genetics or via lifestyle, then I recommend they avoid bioavailable curcuminoids like bioavailable turmeric, black pepper extract.”
Huberman Lab — Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillettat 18:08
Listener reviews
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